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Researchers release OpenTME, a free dataset of 3,634 AI-analyzed cancer tissue samples to advance tumor microenvironment research.

arXiv cs.CVApr 15, 20261 min read
Researchers release OpenTME, a free dataset of 3,634 AI-analyzed cancer tissue samples to advance tumor microenvironment research.

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3 Key Points

  1. OpenTME provides pre-computed tumor microenvironment profiles from 3,634 H&E-stained whole-slide images across five cancer types (bladder, breast, colorectal, liver, and lung) from TCGA

  2. Uses Atlas H&E-TME, an AI-powered pathology application, to perform tissue quality control, segmentation, cell detection/classification, and spatial analysis with 4,500+ quantitative readouts per slide

  3. Dataset available for non-commercial academic research on Hugging Face with plans for future expansion

  4. Enables large-scale, consistent quantitative characterization of tumor microenvironments, which are critical for understanding cancer progression and treatment response

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