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Top Companies' AI MovesTop Companies AIPublished: Oct 16, 2026, 06:31 JST

S&P 500 ends higher as traders shift into Eli Lilly, UnitedHealth

S&P 500 ends higher as traders shift into Eli Lilly, UnitedHealth

3 Key Points

  1. What happened

    The S&P 500 closed up 0.33% at 7,744.06 points, as Eli Lilly gained over 3%, UnitedHealth added 2.8% and Walmart rose 1.4% after Deutsche Bank rating upgrades.

  2. Why it matters

    Eight of the 11 S&P 500 sectors rose, led by healthcare up 1.84%, so the session's gains came from defensive names rather than the AI-linked stocks that have driven most of the index's roughly 13% rise in 2026.

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Context & Analysis

The session's move ran against the pattern that has defined 2026. After hitting a record high the prior week, the S&P 500 remains up about 13% this year, with most of that gain fueled by AI-related stocks. Thursday's winners were healthcare and consumer names instead, and the Philadelphia semiconductor index fell 0.9%, its seventh straight decline.

Behind the rotation sits the cost of borrowing. The yield on 10-year Treasuries retreated but stayed near multiyear highs, and investors worried about inflation tied to high oil prices. "The cost to finance everything, whether it be a new single-family house or a giant data center, is going up, and that has implications for lots of stuff in the stock market," said Jed Ellerbroek, portfolio manager at Argent Capital Management in St. Louis. "The best performing stocks today are the non-cyclical, defensive businesses."

The macro backdrop added to the caution. US producer prices increased by the most in 4-1/2 years in September amid rising goods and services costs, an indication of inflation broadening beyond energy products. Trading was heavy, with 20.7 billion shares changing hands against an average of 17.6 billion over the previous 20 sessions. The S&P 500's roughly 19 times expected earnings valuation, around its lowest since 2023, suggests investors are pricing in an eventual end to the massive earnings growth fueled by AI heavyweights.

FAQ
Which stocks drove the S&P 500's gain?
Eli Lilly gained over 3%, UnitedHealth added 2.8% and Walmart rose 1.4% after rating upgrades by Deutsche Bank. Those three were heavy contributors to the index's gain for the session.
How are AI-related stocks performing?
Several technology stocks fell as investors scrutinized AI-related companies whose debt loads leave them vulnerable to rising interest rates. Dell Technologies dropped 6.9% and Hewlett Packard Enterprise fell 7.1%.
What does the S&P 500's valuation suggest?
The index is trading at about 19 times expected earnings, around its lowest level since 2023. Portfolio manager Jed Ellerbroek said that relatively low valuation suggests investors are pricing in an eventual end to the earnings growth fueled by AI heavyweights.
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